BLID

Entrez Summary: N/A
UniProt Summary: Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death. {ECO:0000269|PubMed:15069058}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cysteine-type endopeptidase activity
positive regulation of endopeptidase activity
positive regulation of peptidase activity
regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity
positive regulation of proteolysis
regulation of endopeptidase activity
regulation of peptidase activity
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
regulation of proteolysis
molecular function
positive regulation of hydrolase activity
apoptotic process
programmed cell death
cell death
mitochondrion
regulation of hydrolase activity
positive regulation of catalytic activity
regulation of apoptotic process
regulation of programmed cell death
positive regulation of cellular protein metabolic process
regulation of cell death
positive regulation of protein metabolic process
positive regulation of molecular function