BNIP2

Entrez Summary: This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
UniProt Summary: Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

CRAL TRIO
BNIP2

polyphosphate catabolic process
exopolyphosphatase activity
polyphosphate metabolic process
positive regulation of muscle cell differentiation
regulation of muscle cell differentiation
nuclear envelope
GTPase activator activity
positive regulation of GTPase activity
regulation of GTPase activity
intracellular membrane-bounded organelle
perinuclear region of cytoplasm
calcium ion binding
positive regulation of hydrolase activity
negative regulation of apoptotic process
negative regulation of programmed cell death
apoptotic process
positive regulation of cell differentiation
negative regulation of cell death
oxoacid metabolic process
organic acid metabolic process
programmed cell death
cell death
regulation of hydrolase activity
positive regulation of developmental process
positive regulation of catalytic activity
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
small molecule metabolic process
organic substance catabolic process
positive regulation of molecular function
cellular catabolic process
regulation of cell differentiation