BOD1L2

Entrez Summary: N/A
UniProt Summary: May play a role in proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles. {ECO:0000250|UniProtKB:Q96IK1}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Tenofovir 10μM R07 exp405	-1.78
Staurosporine 0.02μM R08 exp524	1.76

condensed chromosome outer kinetochore
protein phosphatase 2A binding
protein phosphatase inhibitor activity
spindle microtubule
negative regulation of phosphoprotein phosphatase activity
negative regulation of protein dephosphorylation
condensed chromosome kinetochore
negative regulation of phosphatase activity
negative regulation of dephosphorylation
regulation of phosphoprotein phosphatase activity
spindle pole
regulation of protein dephosphorylation
microtubule organizing center
regulation of phosphatase activity
regulation of dephosphorylation
negative regulation of hydrolase activity
centrosome
cell division
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
negative regulation of protein modification process
negative regulation of catalytic activity
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
negative regulation of molecular function
regulation of hydrolase activity
cell cycle
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of protein modification process