C1QTNF1
Gene Information
- Official Symbol: C1QTNF1
- Official Name: C1q and TNF related 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 114897
- UniProt: Q9BXJ1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Collagen |
| C1q |
GO Terms
| positive regulation of mineralocorticoid secretion |
| positive regulation of aldosterone secretion |
| regulation of aldosterone secretion |
| regulation of mineralocorticoid secretion |
| positive regulation of corticosteroid hormone secretion |
| positive regulation of steroid hormone secretion |
| negative regulation of platelet aggregation |
| protein heterotrimerization |
| negative regulation of homotypic cell-cell adhesion |
| regulation of corticosteroid hormone secretion |
| regulation of platelet aggregation |
| regulation of steroid hormone secretion |
| negative regulation of platelet activation |
| regulation of homotypic cell-cell adhesion |
| regulation of platelet activation |
| regulation of endocrine process |
| negative regulation of blood coagulation |
| negative regulation of hemostasis |
| negative regulation of coagulation |
| protein trimerization |
| positive regulation of lipid transport |
| collagen trimer |
| collagen binding |
| negative regulation of wound healing |
| regulation of blood coagulation |
| regulation of hemostasis |
| positive regulation of lipid localization |
| regulation of coagulation |
| negative regulation of response to wounding |
| protein heterooligomerization |
| regulation of lipid transport |
| regulation of glucose metabolic process |
| positive regulation of hormone secretion |
| regulation of lipid localization |
| regulation of wound healing |
| regulation of cellular carbohydrate metabolic process |
| positive regulation of protein kinase B signaling |
| regulation of response to wounding |
| negative regulation of cell-cell adhesion |
| negative regulation of cell activation |
| regulation of carbohydrate metabolic process |
| regulation of protein kinase B signaling |
| regulation of hormone secretion |
| negative regulation of cell adhesion |
| positive regulation of cytosolic calcium ion concentration |
| regulation of cytosolic calcium ion concentration |
| protein homooligomerization |
| negative regulation of response to external stimulus |
| regulation of cell-cell adhesion |
| positive regulation of secretion by cell |
| regulation of small molecule metabolic process |
| positive regulation of secretion |
| cellular calcium ion homeostasis |
| calcium ion homeostasis |
| cellular divalent inorganic cation homeostasis |
| divalent inorganic cation homeostasis |
| regulation of body fluid levels |
| protein complex oligomerization |
| regulation of hormone levels |
| positive regulation of MAPK cascade |
| cellular metal ion homeostasis |
| regulation of system process |
| metal ion homeostasis |
| cellular cation homeostasis |
| regulation of cell activation |
| cellular ion homeostasis |
| regulation of cell adhesion |
| cation homeostasis |
| inorganic ion homeostasis |
| cellular chemical homeostasis |
| regulation of secretion by cell |
| regulation of MAPK cascade |
| ion homeostasis |
| regulation of secretion |
| cellular homeostasis |
| positive regulation of transport |
| positive regulation of protein phosphorylation |
| positive regulation of intracellular signal transduction |
| positive regulation of phosphorylation |
| regulation of response to external stimulus |
| chemical homeostasis |
| positive regulation of phosphate metabolic process |
| positive regulation of phosphorus metabolic process |
| negative regulation of multicellular organismal process |
| positive regulation of protein modification process |
| integral component of plasma membrane |
| regulation of protein phosphorylation |
| regulation of response to stress |
| protein-containing complex assembly |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| negative regulation of response to stimulus |
| homeostatic process |
| positive regulation of signal transduction |
| positive regulation of protein metabolic process |
| positive regulation of multicellular organismal process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
| protein-containing complex subunit organization |
| regulation of transport |
| positive regulation of gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| PFI-3 10μM R03 exp144 | 1.83 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 1/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 7907
- Expression level (log2 read counts): -0.59
Expression Distribution
C1QTNF1 Expression in NALM6 Cells: -0.59
