CAP2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Phenformin 20μM R05 exp212	-1.9
Rucaparib 6.5μM R08 exp520	-1.9
MS023 7μM R03 exp135	-1.7
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	2.11

CAP N
CAP C

adenylate cyclase binding
activation of adenylate cyclase activity
actin polymerization or depolymerization
cortical actin cytoskeleton
establishment or maintenance of cell polarity
actin filament organization
postsynaptic density
actin binding
supramolecular fiber organization
actin cytoskeleton organization
actin filament-based process
cell morphogenesis
cellular component morphogenesis
identical protein binding
cytoskeleton organization