CAPN7

Entrez Summary: N/A
UniProt Summary: Calcium-regulated non-lysosomal thiol-protease. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

MIT domain binding
self proteolysis
calcium-dependent cysteine-type endopeptidase activity
endopeptidase activity
positive regulation of epithelial cell migration
regulation of epithelial cell migration
positive regulation of cell migration
positive regulation of cell motility
positive regulation of cellular component movement
positive regulation of locomotion
regulation of cell migration
regulation of cell motility
regulation of locomotion
regulation of cellular component movement
proteolysis
positive regulation of multicellular organismal process