CCDC125

Entrez Summary: N/A
UniProt Summary: May be involved in the regulation of cell migration. {ECO:0000269|PubMed:19787194}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of Rho protein signal transduction
negative regulation of Ras protein signal transduction
negative regulation of small GTPase mediated signal transduction
activation of GTPase activity
regulation of Rho protein signal transduction
regulation of Ras protein signal transduction
negative regulation of cell motility
negative regulation of cellular component movement
negative regulation of locomotion
regulation of small GTPase mediated signal transduction
positive regulation of GTPase activity
regulation of GTPase activity
negative regulation of intracellular signal transduction
molecular function
positive regulation of hydrolase activity
regulation of cell motility
regulation of locomotion
regulation of cellular component movement
negative regulation of signal transduction
regulation of hydrolase activity
negative regulation of cell communication
negative regulation of signaling
positive regulation of catalytic activity
negative regulation of response to stimulus
positive regulation of molecular function
regulation of intracellular signal transduction