CCDC174

Gene Information
  • Official Symbol: CCDC174
  • Official Name: coiled-coil domain containing 174
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 51244
  • UniProt: Q6PII3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is found in the nucleus, where it interacts with eukaryotic translation initiation factor 4A, isoform 3. The encoded protein appears to be a part of the exon junction complex, which is involved in RNA processing, translation, and nonsense-mediated mRNA decay. A mutation in this gene has been associated with infantile hypotonia with psychomotor retardation. [provided by RefSeq, Mar 2016].
  • UniProt Summary: Probably involved in neuronal development. {ECO:0000269|PubMed:26358778}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2162
  • Expression level (log2 read counts): 4.84

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1