CD93

Entrez Summary: N/A
UniProt Summary: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

complement component C1q binding
macrophage activation
ficolin-1-rich granule membrane
tertiary granule membrane
specific granule membrane
secretory granule membrane
carbohydrate binding
signaling receptor activity
phagocytosis
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
granulocyte activation
cell-cell adhesion
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
cell surface
leukocyte activation involved in immune response
cell activation involved in immune response
viral process
regulated exocytosis
calcium ion binding
leukocyte mediated immunity
symbiotic process
exocytosis
interspecies interaction between organisms
leukocyte activation
cell adhesion
biological adhesion
secretion by cell
export from cell
cell activation
immune effector process
secretion
immune response
vesicle-mediated transport