CDC123

Entrez Summary: N/A
UniProt Summary: Required for S phase entry of the cell cycle. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 739/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	28/28
bone	26/26
breast	33/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	29/29
uterus	5/5

Expression Distribution

eukaryotic translation initiation factor 2 complex assembly
positive regulation of translational initiation
regulation of translational initiation
positive regulation of translation
cell cycle arrest
positive regulation of cellular amide metabolic process
regulation of translation
regulation of cellular amide metabolic process
cell division
posttranscriptional regulation of gene expression
negative regulation of cell cycle
positive regulation of cell population proliferation
cell cycle process
regulation of cell cycle
cell cycle
protein-containing complex assembly
positive regulation of cellular protein metabolic process
regulation of cell population proliferation
positive regulation of protein metabolic process
protein-containing complex subunit organization
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
positive regulation of biosynthetic process