CDH26

Entrez Summary: N/A
UniProt Summary: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

delta-catenin binding
alpha-catenin binding
cell-cell adhesion mediated by cadherin
catenin complex
CD4-positive, alpha-beta T cell activation
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
alpha-beta T cell activation
cytoskeletal protein binding
beta-catenin binding
adherens junction organization
cell-cell junction assembly
cell-cell adherens junction
integrin binding
cell-cell junction organization
cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules
cell junction organization
T cell activation
cell-cell adhesion via plasma-membrane adhesion molecules
cadherin binding
lymphocyte activation
cell-cell adhesion
cell surface
calcium ion binding
cell morphogenesis
cellular component morphogenesis
protein homodimerization activity
leukocyte activation
cell adhesion
biological adhesion
cell activation