CEACAM5

Entrez Summary: N/A
UniProt Summary: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. {ECO:0000269|PubMed:10864933}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

integral component of external side of plasma membrane
GPI anchor binding
negative regulation of anoikis
negative regulation of myotube differentiation
regulation of anoikis
negative regulation of striated muscle cell differentiation
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
negative regulation of muscle cell differentiation
regulation of myotube differentiation
homotypic cell-cell adhesion
anchored component of membrane
regulation of striated muscle cell differentiation
regulation of muscle cell differentiation
homophilic cell adhesion via plasma membrane adhesion molecules
basolateral plasma membrane
cell-cell adhesion via plasma-membrane adhesion molecules
apical plasma membrane
leukocyte migration
cell-cell adhesion
cell surface
negative regulation of cell differentiation
protein homodimerization activity
negative regulation of apoptotic process
negative regulation of programmed cell death
apoptotic process
cell adhesion
biological adhesion
negative regulation of developmental process
cell migration
negative regulation of cell death
programmed cell death
identical protein binding
cell motility
localization of cell
cell death
locomotion
integral component of plasma membrane
regulation of apoptotic process
movement of cell or subcellular component
regulation of programmed cell death