CETN3

Entrez Summary: N/A
UniProt Summary: Plays a fundamental role in microtubule-organizing center structure and function.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
LB-100 2μM R05 exp210	1.77
Cabazitaxel 0.001μM R05 exp223	2.05

spindle pole body organization
spindle pole body duplication
transcription export complex 2
nuclear pore nuclear basket
centrosome cycle
microtubule organizing center organization
centriole
mRNA transport
microtubule organizing center
RNA transport
nucleic acid transport
establishment of RNA localization
RNA localization
microtubule binding
nucleobase-containing compound transport
microtubule cytoskeleton organization
centrosome
cell division
microtubule-based process
calcium ion binding
nucleolus
cell cycle process
cytoskeleton organization
cell cycle
protein transport
peptide transport
amide transport
establishment of protein localization
nitrogen compound transport