CHDH

Entrez Summary: The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date. [provided by RefSeq, Dec 2010].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

GMC oxred N
GMC oxred C

choline dehydrogenase activity
glycine betaine biosynthetic process
glycine betaine biosynthetic process from choline
glycine betaine metabolic process
choline catabolic process
amino-acid betaine biosynthetic process
choline metabolic process
amino-acid betaine metabolic process
amine catabolic process
cellular biogenic amine catabolic process
neurotransmitter catabolic process
cellular modified amino acid biosynthetic process
cellular biogenic amine metabolic process
cellular amine metabolic process
flavin adenine dinucleotide binding
amine metabolic process
neurotransmitter metabolic process
ammonium ion metabolic process
cellular modified amino acid metabolic process
regulation of neurotransmitter levels
mitochondrial inner membrane
oxidation-reduction process
organonitrogen compound catabolic process
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process
organic substance catabolic process
cellular catabolic process