CNOT11

Gene Information
  • Official Symbol: CNOT11
  • Official Name: CCR4-NOT transcription complex subunit 11
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 55571
  • UniProt: Q9UKZ1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7233
  • Expression level (log2 read counts): 6.17

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1