COL9A3

Entrez Summary: This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3. [provided by RefSeq, Jan 2010].
UniProt Summary: Structural component of hyaline cartilage and vitreous of the eye.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

collagen type IX trimer
extracellular matrix structural constituent conferring tensile strength
female gonad development
development of primary female sexual characteristics
female sex differentiation
extracellular matrix structural constituent
male gonad development
development of primary male sexual characteristics
male sex differentiation
gonad development
development of primary sexual characteristics
extracellular matrix
sex differentiation
endoplasmic reticulum lumen
extracellular matrix organization
collagen-containing extracellular matrix
extracellular structure organization
reproductive structure development
reproductive system development
developmental process involved in reproduction
reproductive process
reproduction
extracellular space
extracellular region