COX7A2

Entrez Summary: N/A
UniProt Summary: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
AICAR 240μM R05 exp211	-2.15
Sucrose 20000μM R06 exp298	1.92

mitochondrial respirasome assembly
mitochondrial respirasome
cytochrome-c oxidase activity
regulation of oxidative phosphorylation
regulation of ATP metabolic process
proton transmembrane transport
regulation of generation of precursor metabolites and energy
electron transport chain
monovalent inorganic cation transport
generation of precursor metabolites and energy
mitochondrion organization
inorganic cation transmembrane transport
cation transmembrane transport
inorganic ion transmembrane transport
cation transport
cellular protein-containing complex assembly
ion transmembrane transport
oxidation-reduction process
transmembrane transport
ion transport
protein-containing complex assembly
regulation of phosphorylation
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
protein-containing complex subunit organization