CPNE3

Entrez Summary: N/A
UniProt Summary: Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation (PubMed:20010870). {ECO:0000269|PubMed:20010870}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Copine
C2

ERBB2 signaling pathway
transporter activity
calcium-dependent phospholipid binding
receptor tyrosine kinase binding
azurophil granule membrane
calcium-dependent protein binding
ERBB signaling pathway
cellular response to calcium ion
response to calcium ion
cellular response to metal ion
glycerophospholipid biosynthetic process
cellular response to inorganic substance
glycerolipid biosynthetic process
phospholipid biosynthetic process
glycerophospholipid metabolic process
protein serine/threonine kinase activity
response to metal ion
phospholipid metabolic process
glycerolipid metabolic process
focal adhesion
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
positive regulation of cell migration
cellular response to growth factor stimulus
neutrophil activation
granulocyte activation
transmembrane receptor protein tyrosine kinase signaling pathway
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
positive regulation of cell motility
response to growth factor
response to inorganic substance
organophosphate biosynthetic process
positive regulation of cellular component movement
cell junction
positive regulation of locomotion
lipid biosynthetic process
myeloid leukocyte activation