CPT1B

Entrez Summary: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

carnitine O-palmitoyltransferase activity
carnitine shuttle
carnitine metabolic process
fatty acid transmembrane transport
amino-acid betaine metabolic process
intracellular lipid transport
fatty acid beta-oxidation
long-chain fatty acid transport
fatty acid transport
fatty acid oxidation
lipid oxidation
mitochondrial transmembrane transport
fatty acid catabolic process
monocarboxylic acid catabolic process
carboxylic acid transmembrane transport
organic acid transmembrane transport
monocarboxylic acid transport
mitochondrial outer membrane
ammonium ion metabolic process
cellular lipid catabolic process
cellular modified amino acid metabolic process
lipid modification
mitochondrial transport
organic acid catabolic process
carboxylic acid catabolic process
anion transmembrane transport
carboxylic acid transport
organic acid transport
lipid transport
lipid catabolic process
lipid localization
fatty acid metabolic process
small molecule catabolic process
organic anion transport
monocarboxylic acid metabolic process
anion transport
carboxylic acid metabolic process
ion transmembrane transport
cellular lipid metabolic process
oxidation-reduction process