CSF2RB

Entrez Summary: The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008].
UniProt Summary: High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

granulocyte macrophage colony-stimulating factor receptor complex
interleukin-5-mediated signaling pathway
interleukin-5 receptor activity
interleukin-3 receptor activity
interleukin-3-mediated signaling pathway
cellular response to interleukin-3
response to interleukin-3
respiratory gaseous exchange by respiratory system
signaling receptor activity
response to lipopolysaccharide
response to molecule of bacterial origin
MAPK cascade
signal transduction by protein phosphorylation
cytokine-mediated signaling pathway
response to bacterium
response to lipid
protein phosphorylation
cellular response to cytokine stimulus
response to cytokine
phosphorylation
response to other organism
response to external biotic stimulus
response to biotic stimulus
integral component of plasma membrane
response to oxygen-containing compound
intracellular signal transduction