CSN3

Entrez Summary: N/A
UniProt Summary: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
A-395N 10μM R05 exp219	1.81
Disulfiram 4.3μM R06 exp281	2.38

lactation
body fluid secretion
mammary gland development
protein stabilization
regulation of protein stability
gland development
regulation of body fluid levels
molecular function
secretion
transmembrane transport
extracellular space
extracellular region