CSRNP3

Entrez Summary: N/A
UniProt Summary: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. Plays a role in apoptosis (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of phosphatase activity
negative regulation of dephosphorylation
regulation of phosphatase activity
regulation of dephosphorylation
sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
negative regulation of hydrolase activity
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
positive regulation of apoptotic process
positive regulation of programmed cell death
DNA-binding transcription factor activity
positive regulation of cell death
negative regulation of catalytic activity
apoptotic process
programmed cell death
cell death
negative regulation of molecular function
positive regulation of transcription by RNA polymerase II
regulation of hydrolase activity
positive regulation of transcription, DNA-templated
regulation of apoptotic process
DNA-binding transcription factor activity, RNA polymerase II-specific
regulation of programmed cell death
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
regulation of cell death
positive regulation of RNA metabolic process
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
positive regulation of biosynthetic process