CTSW

Entrez Summary: N/A
UniProt Summary: May have a specific function in the mechanism or regulation of T-cell cytolytic activity.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Inhibitor I29
Peptidase C1

platelet dense granule lumen
cysteine-type peptidase activity
cysteine-type endopeptidase activity
platelet degranulation
lysosome
proteolysis involved in cellular protein catabolic process
cellular protein catabolic process
protein catabolic process
regulated exocytosis
exocytosis
cellular macromolecule catabolic process
secretion by cell
endoplasmic reticulum
export from cell
macromolecule catabolic process
organonitrogen compound catabolic process
secretion
proteolysis
extracellular space
organic substance catabolic process
cellular catabolic process
immune response
extracellular region
vesicle-mediated transport
membrane