CXADR

Entrez Summary: The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

V-set
I-set

cell adhesive protein binding involved in AV node cell-bundle of His cell communication
AV node cell-bundle of His cell adhesion involved in cell communication
regulation of AV node cell action potential
connexin binding
gamma-delta T cell activation
cardiac muscle cell-cardiac muscle cell adhesion
germ cell migration
AV node cell to bundle of His cell communication
cardiac muscle fiber development
apicolateral plasma membrane
transepithelial transport
epithelial structure maintenance
regulation of cardiac muscle cell action potential
heterotypic cell-cell adhesion
cell communication involved in cardiac conduction
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
regulation of action potential
muscle fiber development
cell adhesion molecule binding
homotypic cell-cell adhesion
cardiac muscle cell development
adherens junction
cardiac cell development
actin cytoskeleton reorganization
regulation of cardiac conduction
filopodium
cell body
virus receptor activity
neutrophil chemotaxis
beta-catenin binding
acrosomal vesicle
PDZ domain binding
cardiac muscle cell differentiation
granulocyte chemotaxis
neutrophil migration
cardiac conduction
viral entry into host cell
granulocyte migration
entry into host
entry into host cell