DCAF13

Entrez Summary: N/A
UniProt Summary: Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000250, ECO:0000269|PubMed:16949367}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Sof1
WD40

Cul4-RING E3 ubiquitin ligase complex
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
small-subunit processome
estrogen receptor binding
maturation of SSU-rRNA
ribosomal small subunit biogenesis
rRNA processing
rRNA metabolic process
ribosome biogenesis
post-translational protein modification
ncRNA processing
ribonucleoprotein complex biogenesis
ncRNA metabolic process
centrosome
cell junction
protein ubiquitination
protein modification by small protein conjugation
nucleolus
RNA processing
protein modification by small protein conjugation or removal
RNA binding
RNA metabolic process
gene expression