DCLK1

Entrez Summary: N/A
UniProt Summary: Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

central nervous system projection neuron axonogenesis
negative regulation of protein localization to nucleus
axon extension
central nervous system neuron axonogenesis
dendrite morphogenesis
neuron projection extension
central nervous system neuron development
developmental cell growth
cell growth
dendrite development
negative regulation of cellular protein localization
developmental growth involved in morphogenesis
regulation of protein localization to nucleus
neuron migration
peptidyl-serine phosphorylation
central nervous system neuron differentiation
peptidyl-serine modification
endosomal transport
protein kinase activity
postsynaptic density
response to virus
protein serine/threonine kinase activity
axonogenesis
forebrain development
developmental growth
growth
axon development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
cell part morphogenesis
regulation of cellular protein localization
cell morphogenesis involved in differentiation
neuron projection development
cell morphogenesis
brain development
head development
neuron development
cellular component morphogenesis