DDX4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Sulforaphane 9μM R08 exp526 no dilution day6	-1.76
Metformin 100 to 150μM on day4 R04 exp170	1.81

DEAD
Helicase C

piRNA biosynthetic process
piP-body
pi-body
P granule
piRNA metabolic process
DNA methylation involved in gamete generation
regulation of transposition
negative regulation of transposition
male meiosis I
DNA methylation
DNA alkylation
male meiotic nuclear division
RNA helicase activity
DNA methylation or demethylation
flagellated sperm motility
sperm motility
gene silencing by RNA
DNA modification
cilium-dependent cell motility
cilium or flagellum-dependent cell motility
meiosis I
meiosis I cell cycle process
gene silencing
meiotic nuclear division
meiotic cell cycle process
nucleic acid binding
meiotic cell cycle
ATPase activity
macromolecule methylation
nuclear division
organelle fission
methylation
cellular process involved in reproduction in multicellular organism
ncRNA metabolic process
spermatogenesis
male gamete generation
gamete generation
perinuclear region of cytoplasm
DNA metabolic process
multicellular organismal reproductive process