DEFB103A

Entrez Summary: N/A
UniProt Summary: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. {ECO:0000269|PubMed:11085990}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

CCR6 chemokine receptor binding
chemoattractant activity
positive chemotaxis
disruption of cells of other organism
killing of cells of other organism
defense response to Gram-negative bacterium
cell killing
defense response to Gram-positive bacterium
Golgi lumen
antimicrobial humoral response
modification of morphology or physiology of other organism
cell chemotaxis
defense response to bacterium
humoral immune response
chemotaxis
taxis
response to bacterium
interspecies interaction between organisms
defense response to other organism
cell migration
cell motility
localization of cell
response to other organism
response to external biotic stimulus
locomotion
response to biotic stimulus
defense response
movement of cell or subcellular component
extracellular space
immune response
extracellular region