DEFB130

Entrez Summary: N/A
UniProt Summary: Antimicrobial host-defense peptide. Has an antiplasmodial activity. {ECO:0000269|PubMed:28181499}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

CCR6 chemokine receptor binding
chemoattractant activity
cell chemotaxis
defense response to bacterium
chemotaxis
taxis
response to bacterium
defense response to other organism
cell migration
localization of cell
cell motility
response to other organism
response to external biotic stimulus
locomotion
response to biotic stimulus
defense response
movement of cell or subcellular component
extracellular space