DGCR6L
Gene Information
- Official Symbol: DGCR6L
- Official Name: DiGeorge syndrome critical region gene 6 like
- Aliases and Previous Symbols: N/A
- Entrez ID: 85359
- UniProt: Q9BY27
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. [provided by RefSeq, Jul 2008].
- UniProt Summary: May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7876
- Expression level (log2 read counts): 3.43
DGCR6L Expression in NALM6 Cells: 3.43
