DLGAP2
Gene Information
- Official Symbol: DLGAP2
- Official Name: DLG associated protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 9228
- UniProt: Q9P1A6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014].
- UniProt Summary: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7264
- Expression level (log2 read counts): -1.69