DZIP1

Entrez Summary: N/A
UniProt Summary: May participate in spermatogenesis via its interaction with DAZ (PubMed:15081113). Has a role in primary cilium formation (PubMed:19852954). {ECO:0000269|PubMed:15081113, ECO:0000269|PubMed:19852954}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
MLN-4924 0.2μM R00 exp21	1.71
Celastrol 0.12μM R05 exp225	1.78

ciliary transition fiber
cytoplasmic sequestering of protein
positive regulation of cilium assembly
protein localization to cilium
smoothened signaling pathway
positive regulation of organelle assembly
regulation of cilium assembly
positive regulation of plasma membrane bounded cell projection assembly
maintenance of protein location
ciliary basal body
centriole
microtubule organizing center
maintenance of location
nucleic acid binding
regulation of plasma membrane bounded cell projection assembly
regulation of cell projection assembly
regulation of protein binding
regulation of organelle assembly
germ cell development
cilium assembly
cellular process involved in reproduction in multicellular organism
cilium organization
regulation of binding
positive regulation of cell projection organization
plasma membrane bounded cell projection assembly
cell projection assembly
positive regulation of cellular component biogenesis
spermatogenesis
male gamete generation
positive regulation of organelle organization
developmental process involved in reproduction
gamete generation
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
protein localization to organelle
organelle assembly
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
regulation of cellular component biogenesis