EHHADH

• Official Symbol: EHHADH
• Official Name: enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
• Aliases and Previous Symbols: N/A
• Entrez ID: 1962
• UniProt: Q08426
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 8617
• Expression level (log2 read counts): 1.43

Expression Distribution

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EHHADH Expression in NALM6 Cells: 1.43