EPB42

• Official Symbol: EPB42
• Official Name: erythrocyte membrane protein band 4.2
• Aliases and Previous Symbols: N/A
• Entrez ID: 2038
• UniProt: P16452
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
• UniProt Summary: Probably plays an important role in the regulation of erythrocyte shape and mechanical properties.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 5950
• Expression level (log2 read counts): 2.0

Expression Distribution

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EPB42 Expression in NALM6 Cells: 2.0