EQTN

Entrez Summary: N/A
UniProt Summary: Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

outer acrosomal membrane
inner acrosomal membrane
acrosomal vesicle exocytosis
fusion of sperm to egg plasma membrane involved in single fertilization
acrosomal membrane
plasma membrane fusion
acrosome reaction
calcium-ion regulated exocytosis
membrane fusion
single fertilization
fertilization
cellular process involved in reproduction in multicellular organism
endocytosis
import into cell
regulated exocytosis
exocytosis
sexual reproduction
multicellular organism reproduction
membrane organization
multi-organism reproductive process
secretion by cell
export from cell
secretion
reproductive process
reproduction
vesicle-mediated transport