EYS

Entrez Summary: The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
UniProt Summary: Required to maintain the integrity of photoreceptor cells. {ECO:0000269|PubMed:18836446}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

interphotoreceptor matrix
detection of light stimulus involved in visual perception
detection of light stimulus involved in sensory perception
skeletal muscle tissue regeneration
detection of visible light
detection of light stimulus
photoreceptor outer segment
tissue regeneration
detection of external stimulus
detection of abiotic stimulus
regeneration
microtubule organizing center
visual perception
sensory perception of light stimulus
response to light stimulus
developmental growth
growth
response to radiation
wound healing
detection of stimulus involved in sensory perception
response to wounding
detection of stimulus
calcium ion binding
molecular function
sensory perception
response to abiotic stimulus
nervous system process
tissue development
system process