FABP7
Gene Information
- Official Symbol: FABP7
- Official Name: fatty acid binding protein 7
- Aliases and Previous Symbols: N/A
- Entrez ID: 2173
- UniProt: O15540
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016].
- UniProt Summary: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16429
- Expression level (log2 read counts): -0.1
FABP7 Expression in NALM6 Cells: -0.1
