FAM3B

Entrez Summary: N/A
UniProt Summary: Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. {ECO:0000269|PubMed:16114871}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

insulin secretion
peptide hormone secretion
hormone secretion
hormone transport
protein secretion
establishment of protein localization to extracellular region
protein localization to extracellular region
signal release
cytokine activity
peptide secretion
glucose homeostasis
carbohydrate homeostasis
regulation of hormone levels
apoptotic process
secretion by cell
export from cell
programmed cell death
cell death
chemical homeostasis
cell-cell signaling
secretion
protein transport
peptide transport
amide transport
establishment of protein localization
homeostatic process
nitrogen compound transport
extracellular region