FAXDC2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Cycloheximide 0.2μM R00 exp15	1.73
Epigallocatechin gallate 20μM R05 exp230	1.79
UM0129480 7μM R02 exp85	1.8
5-Fluorouracil 2μM R00 exp1	1.83
Clomiphene 4.4μM R02 exp68	2

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

C-4 methylsterol oxidase activity
sterol biosynthetic process
steroid biosynthetic process
iron ion binding
sterol metabolic process
organic hydroxy compound biosynthetic process
steroid metabolic process
organic hydroxy compound metabolic process
lipid biosynthetic process
endoplasmic reticulum membrane
oxidation-reduction process
lipid metabolic process
organic cyclic compound biosynthetic process