FBLN2

Entrez Summary: N/A
UniProt Summary: Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108). {ECO:0000269|PubMed:17255108}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
BI-6727 0.0125μM R03 exp97	1.7
6-Thio-2-deoxyguanosine 2μM R06 exp259	1.81

extracellular matrix constituent conferring elasticity
extracellular matrix binding
extracellular vesicle
positive regulation of cell-substrate adhesion
extracellular matrix structural constituent
regulation of cell-substrate adhesion
extracellular matrix
extracellular matrix organization
collagen-containing extracellular matrix
extracellular structure organization
positive regulation of cell adhesion
regulation of cell adhesion
calcium ion binding
extracellular region