FBXO42
Gene Information
- Official Symbol: FBXO42
- Official Name: F-box protein 42
- Aliases and Previous Symbols: N/A
- Entrez ID: 54455
- UniProt: Q6P3S6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. {ECO:0000269|PubMed:19509332}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3429
- Expression level (log2 read counts): 5.24