FBXW5

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

F-box-like
WD40

Cul4-RING E3 ubiquitin ligase complex
regulation of centrosome duplication
regulation of centrosome cycle
SCF ubiquitin ligase complex
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
regulation of mitotic nuclear division
regulation of microtubule cytoskeleton organization
regulation of nuclear division
regulation of microtubule-based process
protein polyubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
proteasomal protein catabolic process
post-translational protein modification
protein kinase binding
ubiquitin-dependent protein catabolic process
modification-dependent protein catabolic process
regulation of cytoskeleton organization
modification-dependent macromolecule catabolic process
proteolysis involved in cellular protein catabolic process
cellular protein catabolic process
regulation of mitotic cell cycle
protein catabolic process
protein ubiquitination
regulation of cell cycle process
protein modification by small protein conjugation
cellular macromolecule catabolic process
protein modification by small protein conjugation or removal
macromolecule catabolic process
organonitrogen compound catabolic process
regulation of cell cycle
proteolysis
regulation of organelle organization
organic substance catabolic process
cellular catabolic process