FCER1A

Gene Information
  • Official Symbol: FCER1A
  • Official Name: Fc fragment of IgE receptor Ia
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 2205
  • UniProt: P12319
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13005
  • Expression level (log2 read counts): -5.6

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1