FCGR2C
Gene Information
- Official Symbol: FCGR2C
- Official Name: Fc fragment of IgG receptor IIc (gene/pseudogene)
- Aliases and Previous Symbols: N/A
- Entrez ID: 9103
- UniProt: P31995
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012].
- UniProt Summary: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16461
- Expression level (log2 read counts): -0.69