FCRL5
Gene Information
- Official Symbol: FCRL5
- Official Name: Fc receptor like 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 83416
- UniProt: Q96RD9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].
- UniProt Summary: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. {ECO:0000269|PubMed:11453668}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11221
- Expression level (log2 read counts): 3.37
FCRL5 Expression in NALM6 Cells: 3.37
