FEZ2

Entrez Summary: N/A
UniProt Summary: Involved in axonal outgrowth and fasciculation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of autophagosome assembly
negative regulation of macroautophagy
regulation of autophagosome assembly
negative regulation of organelle assembly
regulation of vacuole organization
negative regulation of autophagy
regulation of macroautophagy
regulation of organelle assembly
negative regulation of cellular catabolic process
axon guidance
neuron projection guidance
axon
negative regulation of catabolic process
regulation of autophagy
axonogenesis
negative regulation of organelle organization
axon development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
cell part morphogenesis
chemotaxis
taxis
cell morphogenesis involved in differentiation
neuron projection development
negative regulation of cellular component organization
cell morphogenesis
neuron development
cellular component morphogenesis
regulation of cellular catabolic process
regulation of cellular component biogenesis
regulation of catabolic process
neuron differentiation
plasma membrane bounded cell projection organization
cell projection organization
regulation of organelle organization
locomotion
generation of neurons
movement of cell or subcellular component