FGF6

Entrez Summary: N/A
UniProt Summary: Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. {ECO:0000269|PubMed:8663044}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cartilage condensation
cell aggregation
myoblast differentiation
fibroblast growth factor receptor signaling pathway
positive regulation of cell division
sarcolemma
cellular response to fibroblast growth factor stimulus
response to fibroblast growth factor
growth factor activity
positive regulation of protein kinase B signaling
regulation of cell division
cartilage development
regulation of protein kinase B signaling
connective tissue development
skeletal system morphogenesis
angiogenesis
MAPK cascade
signal transduction by protein phosphorylation
blood vessel morphogenesis
muscle structure development
blood vessel development
skeletal system development
cellular response to growth factor stimulus
transmembrane receptor protein tyrosine kinase signaling pathway
vasculature development
cardiovascular system development
response to growth factor
tube morphogenesis
enzyme linked receptor protein signaling pathway
tube development
circulatory system development
anatomical structure formation involved in morphogenesis
positive regulation of cell population proliferation
animal organ morphogenesis
protein phosphorylation
positive regulation of intracellular signal transduction
cellular response to endogenous stimulus
phosphorylation
response to endogenous stimulus
extracellular space