FITM1

Entrez Summary: N/A
UniProt Summary: Plays an important role in lipid droplet accumulation. {ECO:0000269|PubMed:18160536}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of sequestering of triglyceride
regulation of sequestering of triglyceride
lipid droplet organization
positive regulation of lipid storage
lipid storage
regulation of lipid storage
positive regulation of lipid localization
integral component of endoplasmic reticulum membrane
regulation of lipid localization
maintenance of location
phospholipid biosynthetic process
lipid localization
phospholipid metabolic process
organophosphate biosynthetic process
lipid biosynthetic process
molecular function
organophosphate metabolic process
endoplasmic reticulum membrane
cellular lipid metabolic process
lipid metabolic process