GABRA3

Gene Information
  • Official Symbol: GABRA3
  • Official Name: gamma-aminobutyric acid type A receptor subunit alpha3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 2556
  • UniProt: P34903
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008].
  • UniProt Summary: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17473
  • Expression level (log2 read counts): -2.47

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1