GALK2

Entrez Summary: N/A
UniProt Summary: Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. {ECO:0000269|PubMed:16006554}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

N-acetylgalactosamine kinase activity
galactokinase activity
galactose binding
galactose catabolic process via UDP-galactose
galactose catabolic process
galactose metabolic process
carbohydrate phosphorylation
hexose catabolic process
monosaccharide catabolic process
carbohydrate catabolic process
hexose metabolic process
cellular carbohydrate metabolic process
monosaccharide metabolic process
small molecule catabolic process
carbohydrate metabolic process
phosphorylation
ATP binding
small molecule metabolic process
organic substance catabolic process